While the official lineup isn?t set to be announced until April 22nd, the dates for this years ?Rockstar Energy Drink Uproar Festival? have been officially revealed. You can find them below:
08/09 Scranton, PA ? Toyota Pavilion 08/10 Hartford, CT ? The Comcast Theatre 08/11 Darien Center, NY ? Darien Lake Performing Arts Center 08/13 Saratoga Springs, NY ? Saratoga Performing Arts Center 08/14 Mansfield, MA ? Comcast Center 08/16 Bristow, VA ? Jiffy Lube Live 08/17 Holmdel, NJ ? PNC Bank Arts Center 08/18 Wantagh, NY ? Nikon At Jones Beach Theater 08/20 Toronto, ON ? Molson Canadian Amphitheatre 08/22 Tinley Park, IL ? First Midwest Bank Pavilion 08/23 Noblesville, IN ? Klipsch Music Center 08/24 Clarkston, MI ? DTE Energy Music Centre 08/27 Oklahoma City, OK ? Zoo Amphitheater 08/28 Dallas, TX ? Gexa Energy Pavilion 08/29 Woodlands, TX ? Cynthia Woods Mitchell Pavilion 08/31 Albuquerque, NM ? Isleta Amphitheater 09/01 Englewood, CO ? Fiddler?s Green Amphitheater 09/02 Salt Lake City, UT ? USANA Amphitheatre 09/08 Ridgefield, WA ? Sleep County Amphitheatre 09/11 Mountain View, CA ? Shoreline Amphitheatre 09/13 Phoenix, AZ ? Desert Sky Pavilion 09/14 Chula Vista, CA ? Cricket Wireless Amphitheatre 09/15 Irvine, CA ? Verizon Wireless Amphitheatre
Apr. 17, 2013 ? Eggs take a long time to produce in the ovary, and thus are one of a body's precious resources. It has been theorized that the body has mechanisms to help the ovary ensure that ovulated eggs enter the reproductive tract at the right time in order to maximize the chance of successful fertilization.
New research from Carnegie's Allan Spradling and Jianjun Sun has shed light on how successful ovulation and fertilization are brought about by studying these processes in fruit flies. They found that secretions from special glands within the fruit fly's reproductive tract contribute to both ovulation and sperm function, and that this secretion is controlled by a specific hormone receptor gene, called Hr39. Their results suggest that Lrh-1, a mammalian receptor gene closely related to Hr39, also regulates ovulation by controlling reproductive tract secretions in mammals. Their findings are published by eLife.
Sun and Spradling's research provides an example of how the biological processes underlying a specific type of human tissue are often fundamentally similar to the biology of analogous tissues in seemingly very different species, such as insects. These common processes are not an accident, but rather are a consequence of the common evolutionary history of virtually all multicellular organisms on Earth. As a result of these similarities, researchers can genetically manipulate fruit flies in order to identify the genes and pathways controlling a biological process -- in this case ovulation -- and then use genome sequencing to identify the corresponding genes in other species, including humans.
Sun and Spradling began such a strategy a few years ago by characterizing how the glands within the ovary develop. Soon, they were able to tweak normal development to generate flies with anywhere from zero to the normal number of about 200 secretory cells, as well as adults in which secretory cell function could be turned on or off at will. Mice with the same properties would be a much bigger challenge to produce and would yield results much more slowly. Of course, such studies could not be undertaken with humans.
Using these special tools, the researchers confirmed that one important role of reproductive tract secretions is to protect and store sperm. At least 25 secretory cells are required, and their products attract sperm to glands where they can remain safely while bathed in the secretory fluid. Similar storage takes place in a region of the human Fallopian tube known as the isthmus. Sperm are thought to persist in the isthmus for only a few days, but can be stored for a week or more in the case of fruit flies. When production of the secretion is compromised, sperm have difficulty getting to the gland and those that can make it undergo abnormal changes.
The secretory "machinery" studied in these experiments may allow the reproductive tract to signal the ovary when it is ready to receive an egg. Waiting for such a signal before releasing an egg could reduce the chance that an egg would fail to enter the reproductive tract or arrive before active sperm were available.
Interestingly, Spradling and Sun's work shows that different secretions are responsible for ovulation from those responsible for attracting and storing sperm. Identifying the specific secretory cell products (and the corresponding genes) that are required for successful ovulation would be an important step in understanding the mechanisms of this still-mysterious process.
This research has a possible connection to one of the most common forms of ovarian cancer, which was recently shown to derive from abnormalities in reproductive tract secretory cells. The genes and pathways that cells use in carrying out their normal functions are often the targets of the alternations that drive cancer cell growth. Thus, this work should stimulate investigation of the role played by genes such as Lrh1 in this devastating disease.
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The above story is reprinted from materials provided by Carnegie Institution.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
Jianjun Sun, Allan C Spradling. Ovulation in Drosophila is controlled by secretory cells of the female reproductive tract. eLife, 2013 DOI: 10.7554/eLife.00415
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
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How do I implement a frequency counter in a treenode that increases when the user enters an existing word?
I have a program where the user is asked to choose: enter string, search for string
My frequency counter is not working properly. How do I keep track of the frequencies for the left and right nodes? My frequency counter only gives for root:
public void insert(String item){ if(isEmpty()){ root = new TreeNode(item); System.out.println("inserted " + "'" + item + "'" + " into tree. Frequency: " + root.getFreq()); } // If string item already exists, do not insert another node, increase the frequency of the node containing the string else if(searchTree(root,item) == true){ root.upFreq(); System.out.println( "'" + item + "'" + " already exists! Frequency: " + root.getFreq()); //if the string does not already exists, enters string item into new node } else{ root.add(item); System.out.println("inserted " + "'" + item + "'" + " into tree! Frequency: " + root.getFreq()); } }
Replies To: count frequency of strings in java binary tree
#2 baavgai ?
Reputation: 4823
Posts:11,185
Joined:16-October 07
Re: count frequency of strings in java binary tree
Posted 47 minutes ago
Dude! How in the hell can your searchTree be static?!? Tell me TreeNode isn't public...
Your searchTree is, um, disturbing. You should be going left or right, not returning left || right. You call it and seem to expect that root has meaning. It doesn't.
After I had been running at night for more than a decade, a relatively under-the-radar startup called Nextdoor got me to start running during the day. Almost nobody likes to exercise, and for many, overcoming the motivational hump of putting on your shoes and gym clothes can be trying on even the best of days. One evening late in January I had finally overcome this initial barrier to entry, and was just about to stop blogging to do my usual 30-minute nightly sprint when I got the email. “Woman robbed at gunpoint in Dogpatch, San Francisco” the subject line screamed. Unlike many of the emails I constantly receive, this was highly relevant to me, especially because, upon further inspection, the robbery had happened one block from my house. Until this email, I hadn’t given too much thought to Nextdoor , a service that I signed up for at the Allen & Co conference last summer, where co-founder Nirav Tolia had given a talk about the local social network. The company started out as Fanbase in 2009, and was an attempt to create a user-generated content version of ESPN. Founders Tolia and Sarah Leary decided to pivot around May of 2010, and spent the next four to five months testing out different ideas. Fanbase officially pivoted to Nextdoor in September of 2010, starting out its pilot in Lorelei, a neighborhood in Menlo Park. Now a Facebook for your neighborhood, about half the Fanbase funding ended up carrying over, and Tolia and Leary ended up raising an additional $40.2 million for the new Nextdoor product. Initially enthusiastic, I had also invited my neighbors to use the platform, which had resulted in a de facto neighborhood support group (including the services of a pet psychic) when their adventurous cat Kiki went missing. I wrote a post about it for TechCrunch and then sort of forgot about it, rarely logging on to peruse the listings of free stuff and garage sales. Well I was certainly giving the service some thought now: “What if I had been that woman who was robbed?”"What if I had ventured out of my house just 15 minutes earlier?” I was still in my gym clothes, after so much effort, and feeling antsy from my day of work. Worse, I was now worried about a random stranger I had only heard about through the Internet, and I still needed a
Veterinarians at the National Zoo artificially inseminated the zoo's female giant panda Mei Xiang on Saturday after natural breeding failed to occur, zoo keepers said.
Mei Xiang was put under general anesthesia and inseminated with a combination of fresh semen and frozen semen collected from the zoo's male giant panda Tian Tian. The scientists said they planned a second insemination later on Saturday.
Veterinarians detected a rise in hormone levels on Tuesday, indicating Mei Xiang was ready to breed but said "no competent breeding" between the panda pair had occurred.
"We are hopeful that our breeding efforts will be successful this year, and we're encouraged by all the behaviors and hormonal data we've seen so far," said Dave Wildt, head of the Center for Species Survival at the Smithsonian Conservation Biology Institute.
Scientists will continue to monitor Mei Xiang's hormone levels in the coming months and conduct ultrasounds to determine whether she is pregnant. A pregnancy lasts between 95 and 160 days, they said.
Mei Xiang has given birth to two cubs. One died a week after its birth last year. The other was born in 2005 and is now at the China Conservation and Research Center for the Giant Panda in Wolong.
(Reporting by Jane Sutton; editing by Jackie Frank)
(c) Copyright Thomson Reuters 2013. Click For Restrictions - http://about.reuters.com/fulllegal.asp
After I had been running at night for more than a decade, a relatively under-the-radar startup called Nextdoor got me to start running during the day. Almost nobody likes to exercise, and for many, overcoming the motivational hump of putting on your shoes and gym clothes can be trying on even the best of days. One evening late in January I had finally overcome this initial barrier to entry, and was just about to stop blogging to do my usual 30-minute nightly sprint when I got the email. “Woman robbed at gunpoint in Dogpatch, San Francisco” the subject line screamed. Unlike many of the emails I constantly receive, this was highly relevant to me, especially because, upon further inspection, the robbery had happened one block from my house. Until this email, I hadn’t given too much thought to Nextdoor , a service that I signed up for at the Allen & Co conference last summer, where co-founder Nirav Tolia had given a talk about the local social network. The company started out as Fanbase in 2009, and was an attempt to create a user-generated content version of ESPN. Founders Tolia and Sarah Leary decided to pivot around May of 2010, and spent the next four to five months testing out different ideas. Fanbase officially pivoted to Nextdoor in September of 2010, starting out its pilot in Lorelei, a neighborhood in Menlo Park. Now a Facebook for your neighborhood, about half the Fanbase funding ended up carrying over, and Tolia and Leary ended up raising an additional $40.2 million for the new Nextdoor product. Initially enthusiastic, I had also invited my neighbors to use the platform, which had resulted in a de facto neighborhood support group (including the services of a pet psychic) when their adventurous cat Kiki went missing. I wrote a post about it for TechCrunch and then sort of forgot about it, rarely logging on to peruse the listings of free stuff and garage sales. Well I was certainly giving the service some thought now: “What if I had been that woman who was robbed?”"What if I had ventured out of my house just 15 minutes earlier?” I was still in my gym clothes, after so much effort, and feeling antsy from my day of work. Worse, I was now worried about a random stranger I had only heard about through the Internet, and I still needed a